Jumping retroviruses nudge TADs apart
Authors
- M.I. Robson
- S. Mundlos
Journal
- Nature Genetics
Citation
- Nat Genet 51 (9): 1304-1305
Abstract
Far from being junk DNA, the pervasive retrotransposons that populate the genome have a powerful capacity to influence genes and chromatin. A new study demonstrates how the transcription of one such element, HERV-H, can modify the higher-order 3D structure of chromatin during early primate development.